How can we better predict thyroid disruption in humans?

View this webinar to discover the first human-based in vitro thyroid model proven to produce thyroid hormone (T4). Developed in collaboration with the US EPA, the 3D thyroid microtissue assay overcomes the limitations of traditional assays and provides researchers with a robust, human-relevant tool for evaluating chemical disruption of thyroid function.

Key Takeaways:

Learn how a 3D human thyrocyte microtissue assay provides a physiologically relevant platform to evaluate thyroid hormone disruption.
See how the model demonstrated strong reproducibility, dynamic range, and screening precision, establishing confidence for its use in evaluating thyroid-disrupting chemicals (TDCs).
Discover how concentration-response data and statistical benchmarks validate the assay’s robustness for toxicology and chemical screening applications.
Learn how this single in vitro assay can assess multiple molecular initiating events (MIEs), enabling researchers to better prioritize compounds and strengthen human health risk assessment efforts.

Eda Rogers, PhD, is a Research & Development Scientist at LifeNet Health LifeSciences. After obtaining her B.S. degree at the Istanbul University in Turkey where she was Valedictorian, Dr. Rogers graduated with her PhD in Biology from the Rensselaer Polytechnic Institute (RPI). While at RPI, she received the prestigious Karen and Lester Gerhardt Graduate Student Award in recognition of her outstanding academic achievement. Her research interests include developing primary human cell products for use in drug discovery and development. Her latest achievement has been to successfully transfer and improve the 3D thyroid microtissues model from our collaborative team at the US Environmental Protection Agency.