ArthroFlex®
ACELLULAR DERMAL MATRIX
Give soft tissue repair—and your patient’s future—every advantage.

Reinforce Soft Tissue Repair with a Natural Dermal Matrix
ArthroFlex® acellular dermal matrix is designed to reinforce challenging soft tissue repairs while preserving the native collagen architecture that supports biologic integration.¹,²
Derived from donated human dermis and processed to remove donor cellular components, ArthroFlex maintains the natural extracellular matrix structure that supports tissue remodeling and repair reinforcement.¹
Clinical Applications in Practice
Clinical case studies demonstrate the use of dermal matrix augmentation to reinforce rotator cuff repairs and other soft tissue reconstructions in challenging clinical environments.¹,⁴
These cases illustrate how dermal scaffolds may support repair constructs while allowing biologic incorporation of the graft.⁵
Designed for challenging repairs
Supporting cellular infiltration and tissue remodeling over time⁵, ArthroFlex helps to give patients a healing advantage.
- Structural reinforcement for soft tissue repairs
- Preserved dermal collagen architecture
- Decellularized for biocompatibility
- Biologic scaffold supporting tissue integration¹,²
Surgeon Experience with Dermal Matrix Augmentation
Dermal matrices are commonly used by orthopedic surgeons to reinforce repairs in cases involving compromised tissue quality or large tears.⁴
Augmentation with dermal matrices may provide additional structural support to repair constructs during the critical healing phase, particularly in revision procedures or large rotator cuff repairs.⁴
Evidence Supporting Dermal Matrix Augmentation
Better Structural Outcomes
Clinical studies evaluating extracellular matrix augmentation in rotator cuff repair have demonstrated improved structural outcomes compared with repair alone in large or massive tears.³
Lower Re-tear Rates
In one prospective comparative study, rotator cuff repairs augmented with extracellular matrix grafts demonstrated lower re-tear rates compared with non-augmented repairs.³
Improved Structural Integrity
Dermal matrix augmentation has also been associated with improvements in structural integrity and patient-reported outcomes in challenging repair environments.⁴
Versatile Across Soft Tissue Reconstruction
Dermal matrices are used across a range of orthopedic procedures where reinforcement of soft tissue repairs may be beneficial.⁴
- Rotator cuff augmentation
- Tendon reinforcement
- Ligament reconstruction
- Revision soft tissue repairs
references
- LifeNet Health. ArthroFlex® Acellular Dermal Matrix product information.
- Arthrex. ArthroFlex® Dermal Allograft product overview.
- Gilot GJ, Alvarez-Pinzon AM, Barcksdale L, Westerdahl D, Krill M. Outcome of large to massive rotator cuff tears repaired with and without extracellular matrix augmentation. Arthroscopy.
- Reviews and surgical technique publications describing dermal matrix augmentation in rotator cuff repair and sports medicine procedures.
- Literature describing acellular dermal matrices as biologic scaffolds supporting cellular infiltration and vascularization.